Endoscopic Mucosectomy Case Study 2: Large Colon Adenoma


A 54-year old female who underwent screening colonoscopy was found to have a 5 cm adenomatous growth encompassing the hemicircumference of the sigmoid colon. Biopsies showed a tubular-villous adenoma. She was referred for mucosectomy.


Endoscopic ultrasonography showed thickening of the mucosa with preservation of the submucosa and muscularis propria layers. Saline-assisted piecemeal mucosectomy was performed without complication.


Surveillance sigmoidoscopy three months later showed scarring at the site of the previous mucosectomy with no residual or recurrent adenoma.